What are the symptoms of ITP? Some people with ITP, especially those with a count over 50, may have no symptoms at all, and their ITP only noticed during a routine blood test. Even people with very low counts, can sometimes have few symptoms. Common symptoms are: petechiae pinprick rash of blood spots bruising nosebleeds gum bleeds black mouth blisters fatigue heavy periods. Rare symptoms are: blood in the eyes bleeding from the ears blood in the urine bleeding from the gut bleed into the brain.
How is ITP treated? Some adults with mild ITP may not need any treatment, but will be monitored with occasional blood tests. There is no cure for ITP and treatment is used to raise the platelet count to counteract symptoms. First line treatments include prednisolone and intravenous immunoglobulin under various brand names. Treatment for ITP includes time and close observation. In some cases, ITP goes away by itself. In cases where the platelet count is very low or there is evidence of bleeding, some form of treatment should be started.
First-line treatments the preferred treatments, or the ones that are tried first for ITP include:. Occasionally, a person who appears to have been cured of ITP will experience a relapse, perhaps months or even years after the initial episode. If this happens the person will need repeat treatment. In most cases, the relapse seems to be triggered by a viral infection. This page has been produced in consultation with and approved by:.
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Drinking plenty of water will actually help your kidneys to flush out excess fluid. Fluid retention may be a sign of disease. Content on this website is provided for information purposes only. Information about a therapy, service, product or treatment does not in any way endorse or support such therapy, service, product or treatment and is not intended to replace advice from your doctor or other registered health professional. People who undergo splenectomy may be given certain antibiotics or vaccines that lessen but do not totally eliminate the infection risk.
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The Manual was first published in as a service to the community. Learn more about our commitment to Global Medical Knowledge. This site complies with the HONcode standard for trustworthy health information: verify here. Common Health Topics. Platelet Disorders. Test your knowledge. Neutropenia is the term for an abnormally low number of neutrophils, a type of white blood cell in the blood.
Which of the following is often the first indication that a person has neutropenia? More Content. Click here for the Professional Version. People may have tiny purple spots on their skin petechiae and bleed easily. Corticosteroids or other drugs are given to block the destruction of platelets.
In adults, ITP is usually long lasting chronic. The authors of a recently published review discussed current hypotheses and their scientific basis.
Patients with ITP have increased concentrations of circulating platelet microparticles PMP , which protect against bleeding. PMPs are small vesicles 0. Numerous studies show that PMPs are more abundant in patients with ITP than in patients with other thrombocytopenic conditions or healthy controls. Studies have also shown that PMPs have procoagulant activity. Clinically, elevated PMP levels are associated with risk of arterial thrombosis and other medical conditions associated with thrombosis.
Nevertheless, patients with ITP are obviously at risk for bleeding, although severe bleeding is relatively rare.
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